Chromatography Standards
Medchemexpress LLC Diclofenac ethyl ester | 15307-77-4 | 99.3% | 100 MG
Diclofenac ethyl ester is a prodrug of Diclofenac, designed for enhanced delivery. It is encapsulated in polymer micelles in vitro and released with prolonged circulation time and reduced drug concentrations in the heart and kidneys in vivo.
- Prodrug of Diclofenac
- Encapsulated in polymer micelles
- Prolonged circulation time
- Reduced drug concentrations in heart and kidneys
Medchemexpress LLC Cpd-10 | 3055471-57-0 | 96.7% | 888.07 | 50 MG
CPD-10 is a potent CCND1 and CDK4 PROTAC degrader that exhibits anti-proliferation effects and induces apoptosis. It decreases the protein expression of cyclin D1, cyclin D3, CDK4, and P-Rb(5807/811) in a dose-dependent manner. This compound is composed of a CDK ligand, an E3 Ligase Ligand-Linker Conjugates ligand, and a linker.
- Potent CCND1 and CDK4 PROTAC degrader
- Shows anti-proliferation
- Induces apoptosis
- Decreases protein expression of cyclin D1, cyclin D3, CDK4, P-Rb(5807/811) in a dose-dependent manner
Medchemexpress LLC Ibiglustat (succinate) | 1629063-80-4 | 99.7% | 507.57 | 25 MG
Ibiglustat succinate is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. It can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease.
- Orally active
- Brain-penetrant glucosylceramide synthase (GCS) inhibitor
- Can prevent additional GL-3 accumulation in Fabry disease cells
Medchemexpress LLC Folic acid (standard) | 59-30-3 | 98.4% | 441.40 | 100 MG
Folic acid (Standard) is the analytical standard of Folic acid, intended for research and analytical applications. Folic acid (Vitamin B9) is an orally active essential nutrient from the B complex group of vitamins. It shows antidepressant-like effects and its sodium form reduces the risk of neonatal neural tube defects. It can be used in the research of megaloblastic and macrocytic anemias due to folic deficiency.
- Analytical standard for assays
- Used in qualitative, quantitative, and methodological research experiments
- Shows antidepressant-like effect
- Reduces the risk of neonatal neural tube defects (sodium form)
- Used for research of megaloblastic and macrocytic anemias due to folic deficiency
Medchemexpress LLC Suplatast (Tosilate) | 94055-76-2 | 99.7% | 499.64 | 1 G
Suplatast Tosilate (IPD 1151T) is an orally active Th2 cytokine inhibitor that can inhibit both IL-4 and IL-5 production from Th2 cells and suppress IgE synthesis. It acts as an anti-allergic agent with antiasthmatic, anti-inflammatory, and antifibrotic activity.
- Orally active Th2 cytokine inhibitor
- Inhibits IL-4 and IL-5 production from Th2 cells
- Suppresses IgE synthesis
- Anti-allergic agent
- Antiasthmatic activity
- Anti-inflammatory activity
- Antifibrotic activity
Apexbio Technology LLC Oxytetracycline (Terramycin) 79-57-2 10mM (in 1mL DMSO)
Oxytetracycline (Terramycin) (CAS 79-57-2) is a small-molecule inhibitor targeting bacterial protein synthesis It is designed to inhibit aminoacyl-tRNA binding to the 30S ribosomal subunit thereby interfering with bacterial protein synthesis Oxytetracycline exerts its biological activity primarily through reversible binding to the bacterial 30S ribosomal subunit inhibiting protein biosynthesis In in vitro studies Oxytetracycline demonstrates bacteriostatic activity against Gram-positive and Gram-negative bacteria with an IC50 value typically ranging between 0 1 10 g/mL depending on the tested microorganism and experimental system Based on these pharmacological properties Oxytetracycline holds research potential in microbiological studies to suppress contaminating bacteria and in cell culture research for maintaining sterile conditions or selecting antibiotic-resistant cell populations
Sigma Aldrich Fine Chemicals Biosciences Galantamine hydrobromide European Pharmacopoeia (EP) Reference Standard | 1953-04-4 | MFCD26142877 |
Galantamine hydrobromide European Pharmacopoeia (EP) Reference Standard | Mol Wt: 368.27 | 1953-04-4 | MFCD26142877 |
Medchemexpress LLC Naproxen (Standard) | 22204-53-1 | C14H14O3 | 100 MG
Naproxen (Standard) is an analytical and reference standard for research and analytical applications. This compound functions as a COX-1 and COX-2 inhibitor, with IC50s of 8.72 and 5.15 μM, respectively, in cell assays. It is commonly used in qualitative, quantitative, and methodological research experiments, including techniques such as HPLC, GC, and MS.
- High purity of 99.91%
- Inhibits both COX-1 and COX-2 enzymes
- Suitable as an analytical and reference standard
TARGETMOL CHEMICALS INC Nitisinone 100MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 500 mg and bulk. Please contact Fisher for quotes. Nitisinone (SC0735)(SC0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor. Purity 99.54%
Cayman Chemical Flurbiprofen-d3, Purity: ≥99% deuterated forms (d1-d3), CAS: 1185133-81-6, 5 mg
An internal standard for the quantification of flurbiprofen by GC- or LC-MS
Apexbio Technology LLC Eltrombopag Olamine 496775-62-3 500mg
Eltrombopag Olamine is an orally bioavailable thrombopoietin receptor (c-mpl) agonist that directly stimulates platelet production through activation of the JAK2/STAT signaling pathway In cellular assays using murine BAF3 cells expressing human thrombopoietin receptor (hTpoR) eltrombopag induced STAT-dependent signaling responses with an EC50 value of approximately 0 27 M This compound promotes differentiation of human CD34 progenitor cells into megakaryocytes capable of platelet production Eltrombopag is commonly applied in hematological research particularly in studies involving thrombocytopenia and thrombopoiesis-related mechanisms
Sigma Aldrich Fine Chemicals Biosciences (E)-Thiothixene United States Pharmacopeia (USP) Reference Standard | 3313-27-7 | 100MG
(E)-Thiothixene United States Pharmacopeia (USP) Reference Standard | Mol Wt: 443.63 | 3313-27-7 | 100MG
Sigma Aldrich Fine Chemicals Biosciences Paclitaxel European Pharmacopoeia (EP) Reference Standard | 33069-62-4 | MFCD00869953
Paclitaxel European Pharmacopoeia (EP) Reference Standard | Mol Wt: 853.91 | 33069-62-4 | MFCD00869953